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Microsoft Research

Technology and AI 359,000 subscribers

Genetic Screens with CRISPR: A New Hope in Functional Genomics

15.10.2019 3,371 views
Published: 15.10.2019 Category: Technology and AI Views: 3,371

Episode details

Episode description

Functional genomics attempts to understand the genome by disrupting the flow of information from DNA to RNA to protein and then observing how the cell or organism changes in response. Both RNAi and CRISPR technologies are simply hacks of systems that originally evolved to silence viruses, reprogrammed to target genes we’re interested in studying, as decoding the function of genes is a critical step towards understanding how gene dysfunction leads to disease. Here we will discuss the development and optimization of CRISPR technology for genome-wide genetic screens and its application to multiple biological problems.

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